Oriveda PSP-50 was prepared in China using the original patented methods. Its properties are the properties of the original ratified PSP medicine, with the only real difference being a higher level of actives, the result of 21st century pharmaceutical techniques.
In contrast with the Asian products ORIVeDA specifies the level of polypeptides plus the percentage of Beta-D-glucans: in our latest batch over 40% were bioactive Beta-D-glucans (this includes both (1>3)(1>6) and (1>4)(1>6)Beta-D-glucans with 100% bio-availability).
The (1>4)(1>6)Beta-D-glucans (unique for Coriolus versicolor) cannot be listed separately because no standardised analytical procedure exists currently.
Non-extracted mushroom products are mostly indigestible by humans, since mushrooms are made of chitin, not cellulose, like plants. Heat is needed to break the chitin cell walls and to release the bioactives. Most of the time hot water is used to start the extraction process.
Full information about extraction and why it is absolutely necessary with mushroom products can be found here. An objective, easy-to-follow guideline on how to separate the bad from the reliable mushroom supplements can be found here (also reveals why it’s best not to spend your money on tinctures..).
This monograph is mainly based on the following literature:
-PSP in clinical cancer therapy – A brief overview of Phase I, II and III trials – Prof. Qing-yao Yang – Shanghai Teachers Academy, 2000
-Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production – Jian Cui, Yusuf Chisti – Biotechnology Advances 21 (2003) 109–122
-PSP and PSK – Shanghai Teachers University
These publications and many others can be found, free for download, here.